EPRISTERIDE UV
Epristeride
CAS: 119169-78-7
Molecular Formula: C25H37NO3
EPRISTERIDE UV - Names and Identifiers
EPRISTERIDE UV - Physico-chemical Properties
| Molecular Formula | C25H37NO3 |
| Molar Mass | 399.57 |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Melting Point | 242-249° |
| Boling Point | 596.0±50.0 °C(Predicted) |
| pKa | 4.8(at 25℃) |
| Storage Condition | 2-8℃ |
| Physical and Chemical Properties | White crystals are obtained from ethyl acetate with a melting point of 242~249 ℃. pK4.8. |
| Use | It is a treatment for benign prostatic hyperplasia. It is a strong inhibitor of type 2 sterol 5 α-reductase and has weak inhibitory power on type 1 enzyme. Testosterone reductase inhibitors. |
EPRISTERIDE UV - Upstream Downstream Industry
EPRISTERIDE UV - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.503 ml | 12.514 ml | 25.027 ml |
| 5 mM | 0.501 ml | 2.503 ml | 5.005 ml |
| 10 mM | 0.25 ml | 1.251 ml | 2.503 ml |
| 5 mM | 0.05 ml | 0.25 ml | 0.501 ml |
Last Update：2024-01-02 23:10:35
EPRISTERIDE UV - Introduction
Biological activity
Epristeride is a new type of 5 α-reductase inhibitor.
Target
5α-reductase
Chemical properties
white crystal from ethyl acetate, melting point 242~249 ℃. pK4.8.
Production method
3-oxoandrost-4-ene-17 β-carboxylic acid methyl ester (Ⅰ) is treated with phosphorus tribromide in glacial acetic acid, converted into compound (Ⅱ), and then hydrolyzed into compound (Ⅲ). First react with oxalyl chloride, and then tert-butylamine is quenched to obtain compound (Ⅳ). (Ⅳ) After treatment with ethyl magnesium bromide, adding sec-butyl lithium, and using carbon dioxide for halogen metal exchange reaction, the crude product of eriandrostine is obtained. The crude product can be heated and refined in ethyl acetate.
Last Update：2024-04-10 22:29:15
EPRISTERIDE UV - Reference Information
| biological activity | Epristeride is a new type of 5 α-reductase inhibitor. |
| target | 5α-reductase |
| chemical properties | white crystal from ethyl acetate, melting point 242~249 ℃. pK4.8. |
| use | is a therapeutic drug for benign prostatic hyperplasia. It is a strong inhibitor of type 2 sterol 5 α-reductase and has weak inhibitory power on type 1 enzyme. Testosterone reductase inhibitor. |
| Production method | 3-oxoandrost-4-ene-17 β-carboxylic acid methyl ester (Ⅰ) is treated with phosphorus tribromide in glacial acetic acid, converted into compound (Ⅱ), and then hydrolyzed into compound (Ⅲ). First react with oxalyl chloride, and then tert-butylamine is quenched to obtain compound (Ⅳ). (Ⅳ) After treatment with ethyl magnesium bromide, adding sec-butyl lithium, and using carbon dioxide for halogen metal exchange reaction, the crude product of eriandrostine is obtained. The crude product can be heated and refined in ethyl acetate. |
Last Update：2024-04-09 19:05:05
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Multiple SpecificationsSpot supply
Product Name: ONO-9302; SKF105657 Visit Supplier Webpage Request for quotationCAS: 119169-78-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
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Mobile: 609-228-6898
Spot supply
Product Name: Epristeride Visit Supplier Webpage Request for quotationCAS: 119169-78-7
Tel: +86-400-900-4166
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Mobile: +86-18621343501
QQ: 2881950922
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Product Name: Epristeride Visit Supplier Webpage Request for quotationCAS: 119169-78-7
Tel: +86-18821248368
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Mobile: +86-18821248368
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Product Name: Epristeride Visit Supplier Webpage Request for quotation
CAS: 119169-78-7
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CAS: 119169-78-7
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View History
EPRISTERIDE UV
1,4-联苯基丁烷
3-PYRROLIDINEPROPANAMIDE, 伪-AMINO-2-OXO-, HYDROCHLORIDE
(S)-2-乙酰氨基-4-((叔丁氧羰基)氨基)丁酸
N-{4-[(4-METHOXYANILINO)CARBONYL]PHENYL}-2-OXO-1-OXASPIRO[4.5]DECANE-4-CARBOXAMIDE
N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE
2-氯-3-甲基吡啶-5-硼酸 (含不同量的酸酐)
4-[[[(3-CHLORO-4-ETHOXYBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
Vecuronium intermediate 6
2-脱氧-2-氟-ALPHA-D-阿拉伯呋喃糖基溴化物 3,5-二苯甲酸酯
1,4-联苯基丁烷
3-PYRROLIDINEPROPANAMIDE, 伪-AMINO-2-OXO-, HYDROCHLORIDE
(S)-2-乙酰氨基-4-((叔丁氧羰基)氨基)丁酸
N-{4-[(4-METHOXYANILINO)CARBONYL]PHENYL}-2-OXO-1-OXASPIRO[4.5]DECANE-4-CARBOXAMIDE
N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE
2-氯-3-甲基吡啶-5-硼酸 (含不同量的酸酐)
4-[[[(3-CHLORO-4-ETHOXYBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
Vecuronium intermediate 6
2-脱氧-2-氟-ALPHA-D-阿拉伯呋喃糖基溴化物 3,5-二苯甲酸酯
Raw Materials for EPRISTERIDE UV